It depends entirely on the grounds raised. Non-substantive issues, such as missing information, incorrect owner details, and specimen deficiencies, are generally straightforward to resolve and carry a high success rate.
Substantive issues are more complicated. A likelihood of confusion refusal where the earlier mark is very similar and the goods and services closely overlap can be very difficult to overcome; one where the similarity is marginal, or the classes are clearly different, is more tractable. A descriptiveness refusal on a genuinely descriptive mark is hard to overcome without evidence of acquired distinctiveness; one where the mark is only borderline descriptive may be argued successfully.
A realistic assessment of the specific grounds is the starting point before committing to a response. Start with a free assessment of your office action with Trama.